FisMat2017 - Submission - View

Abstract's title: Maximum-entropy modelling of biomolecules
Submitting author: Guido Tiana
Affiliation: Università degli Studi di Milano
Affiliation Address: Department of Physics via Celoria 16 20133 Milano
Country: Italy
Oral presentation/Poster (Author's request): Oral presentation
Other authors and affiliations:
Abstract

An useful step to understand the function of biomolecules is to model their conformations and the fluctuations among them. Experiments always provide a partial view of the conformational properties of complex molecules. The principle of maximum entropy is a powerful tool to build molecular models based on experimental data, using all and only the information available. We will describe the application of this principle to obtain interaction potentials for chromatin and proteins, and use this potential to explore the associated conformational space.